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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
24.55
Human Site:
S336
Identified Species:
45
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
S336
K
P
G
S
Q
L
D
S
M
L
G
S
L
Q
S
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
S334
K
P
G
S
Q
L
D
S
M
L
G
S
L
Q
S
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
V329
V
A
T
V
A
K
G
V
C
G
A
C
K
K
P
Dog
Lupus familis
XP_543425
664
72715
S409
K
P
G
S
Q
L
D
S
M
L
G
S
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
S336
K
P
G
S
Q
L
D
S
M
L
G
S
L
Q
S
Rat
Rattus norvegicus
Q66H76
586
64001
S331
K
P
G
S
Q
L
D
S
M
L
G
S
L
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
G324
G
V
A
T
V
A
K
G
V
C
G
A
C
K
K
Frog
Xenopus laevis
Q2TCH4
506
55983
V284
Q
R
P
I
A
G
Q
V
V
T
A
L
G
H
T
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
D197
V
T
D
P
G
F
A
D
R
Y
H
P
D
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
S326
S
R
E
D
Q
L
D
S
M
L
G
N
L
Q
A
Honey Bee
Apis mellifera
XP_624308
559
62451
N308
Q
L
D
S
M
L
G
N
L
Q
A
D
M
S
R
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
L191
I
G
Q
V
V
I
A
L
G
K
M
W
H
P
E
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
S440
S
Q
P
S
Q
L
D
S
M
L
G
H
L
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
6.6
0
6.6
N.A.
60
13.3
0
66.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
33.3
20
13.3
N.A.
73.3
40
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
16
8
16
0
0
0
24
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
8
8
0
0
% C
% Asp:
0
0
16
8
0
0
54
8
0
0
0
8
8
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
39
0
8
8
16
8
8
8
62
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
0
% H
% Ile:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
39
0
0
0
0
8
8
0
0
8
0
0
8
24
8
% K
% Leu:
0
8
0
0
0
62
0
8
8
54
0
8
54
0
0
% L
% Met:
0
0
0
0
8
0
0
0
54
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
39
16
8
0
0
0
0
0
0
0
8
0
8
8
% P
% Gln:
16
8
8
0
54
0
8
0
0
8
0
0
0
47
0
% Q
% Arg:
0
16
0
0
0
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
16
0
0
54
0
0
0
54
0
0
0
39
0
8
54
% S
% Thr:
0
8
8
8
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
16
8
0
16
16
0
0
16
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _